PRODUCTION AND PURIFICATION OF HIGH-TITER NEWCASTLE DISEASE VIRUS FOR USE IN PRECLINICAL MOUSE MODELS OF CANCER

Production and Purification of High-Titer Newcastle Disease Virus for Use in Preclinical Mouse Models of Cancer

Newcastle disease virus (NDV) is a single-stranded, negative-sense RNA virus in the Paramyxoviridae family.Although primarily an avian pathogen, NDV is a potent oncolytic virus that has been shown jmannino.com to be safe and effective in a variety of preclinical cancer models and human clinical trials.To produce virus for oncolytic trials, NDV is c

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Abundance and Diversity of Ophiostomatoid Fungi Associated With the Great Spruce Bark Beetle (Dendroctonus micans) in the Northeastern Qinghai-Tibet Plateau

The role of several virulent tree pathogens in host death has been overlooked because of the aggressiveness of their associated bark beetles.The great spruce bark beetle (Dendroctonus micans) is a replica beach walk candle widely distributed beetle that infests coniferous plants in Eurasia; however, its associated fungi have been poorly studied.The

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